Dr Greg James
Senior Research Assistant
Principal Research Molecular Biologist
School of Health and Rehabilitation Sciences
+61 7 334 66037
+61 7 336 54753
Journal Articles
James, Greg, Ahern, Ben, Goodwin, Wendy, Goss, Ben and Hodges, Paul (2025). Correction to: ISSLS Prize in Basic Science 2025: Structural changes of muscle spindles in the multifidus muscle after intervertebral disk injury are resolved by targeted activation of the muscle. European Spine Journal, 34 (5), 2046-2046. doi: 10.1007/s00586-025-08744-w
James, Greg, Ahern, Ben, Goodwin, Wendy, Goss, Ben and Hodges, Paul (2025). Structural changes of muscle spindles in the multifidus muscle after intervertebral disk injury are resolved by targeted muscle activation. European Spine Journal, 34 (5), 1-1. doi: 10.1007/s00586-025-08646-x
James, G., Ahern, B. J., Goodwin, W., Goss, B. and Hodges, P. W. (2024). Targeted multifidus muscle activation reduces fibrosis of multifidus muscle following intervertebral disc injury. European Spine Journal, 33 (6), 2166-2178. doi: 10.1007/s00586-024-08234-5
James, Gregory, Stecco, Carla, Blomster, Linda, Hall, Leanne, Schmid, Annina B., Shu, Cindy C., Little, Christopher B., Melrose, James and Hodges, Paul W. (2022). Muscle spindles of the multifidus muscle undergo structural change after intervertebral disc degeneration. European Spine Journal, 31 (7), 1879-1888. doi: 10.1007/s00586-022-07235-6
James, Gregory, Millecamps, Magali, Stone, Laura S. and Hodges, Paul W. (2021). Multifidus muscle fiber type distribution is changed in mouse models of chronic intervertebral disc degeneration, but is not attenuated by whole body physical activity. Spine, 46 (23), 1612-1620. doi: 10.1097/BRS.0000000000004105
Klyne, David M., Barbe, Mary F., James, Greg and Hodges, Paul W. (2021). Does the interaction between local and systemic inflammation provide a link from psychology and lifestyle to tissue health in musculoskeletal conditions?. International Journal of Molecular Sciences, 22 (14) 7299, 1-21. doi: 10.3390/ijms22147299
Chen, Xiaolong, Hodges, Paul W., James, Gregory and Diwan, Ashish D. (2020). Do Markers of Inflammation and/or Muscle Regeneration in Lumbar Multifidus Muscle and Fat Differ between Individuals with Good or Poor Outcome Following Microdiscectomy for Lumbar Disc Herniation?. Spine, 46 (10), 678-686. doi: 10.1097/BRS.0000000000003863
James, Greg, Chen, Xiaolong, Diwan, Ashish and Hodges, Paul W. (2020). Fat infiltration in the multifidus muscle is related to inflammatory cytokine expression in the muscle and epidural adipose tissue in individuals undergoing surgery for intervertebral disc herniation. European Spine Journal, 30 (4), 837-845. doi: 10.1007/s00586-020-06514-4
James, G., Klyne, D. M., Millecamps, M., Stone, L. S. and Hodges, P. W. (2019). ISSLS Prize in Basic science 2019: physical activity attenuates fibrotic alterations to the multifidus muscle associated with intervertebral disc degeneration. European Spine Journal, 28 (5), 893-904. doi: 10.1007/s00586-019-05902-9
Lawrenson, P. R., Crossley, K. M., Vicenzino, B. T., Hodges, P. W., James, G., Croft, K. J., King, M. G. and Semciw, A. I. (2019). Muscle size and composition in people with articular hip pathology: a systematic review with meta-analysis. Osteoarthritis and Cartilage, 27 (2), 181-195. doi: 10.1016/j.joca.2018.10.008
James, Gregory, Millecamps, Magali, Stone, Laura S. and Hodges, Paul W. (2018). Dysregulation of the inflammatory mediators in the multifidus muscle after spontaneous intervertebral disc degeneration SPARC-null mice is ameliorated by physical activity. Spine, 43 (20), E1184-E1194. doi: 10.1097/BRS.0000000000002656
James, Gregory, Sluka, Kathleen A., Blomster, Linda, Hall, Leanne, Schmid, Annina B., Shu, Cindy C., Little, Christopher B., Melrose, James and Hodges, Paul W. (2018). Macrophage polarization contributes to local inflammation and structural change in the multifidus muscle after intervertebral disc injury. European Spine Journal, 27 (8), 1744-1756. doi: 10.1007/s00586-018-5652-7
James, Gregory, Blomster, Linda, Hall, Leanne, Schmid, Annina B., Shu, Cindy C., Little, Christopher B., Melrose, James and Hodges, Paul W. (2016). Mesenchymal stem cell treatment of intervertebral disc lesion prevents fatty infiltration and fibrosis of the multifidus muscle, but not cytokine and muscle fiber changes. Spine, 41 (15), 1208-1217. doi: 10.1097/BRS.0000000000001669
Hodges, Paul W., James, Gregory, Blomster, Linda, Hall, Leanne, Schmid, Annina, Shu, Cindy, Little, Chris and Melrose, James (2015). Multifidus muscle changes after back injury are characterized by structural remodeling of muscle, adipose and connective tissue, but not muscle atrophy molecular and morphological evidence. Spine, 40 (14), 1057-1071. doi: 10.1097/BRS.0000000000000972
Hodges, Paul W., James, Gregory, Blomster, Linda, Hall, Leanne, Schmid, Annina B., Shu, Cindy, Little, Chris and Melrose, James (2014). Can proinflammatory cytokine gene expression explain multifidus muscle fiber changes after an intervertebral disc lesion?. Spine, 39 (13), 1010-1017. doi: 10.1097/BRS.0000000000000318
James, G., Key, B. and Beverdam, A. (2014). The E3 ubiquitin ligase Mycbp2 genetically interacts with Robo2 to modulate axon guidance in the mouse olfactory system. Brain Structure and Function, 219 (3), 861-874. doi: 10.1007/s00429-013-0540-8
James, Gregory, Foster, Simon R., Key, Brian and Beverdam, Annemiek (2013). The expression pattern of EVA1C, a novel slit receptor, is consistent with an axon guidance role in the mouse nervous system. PLoS One, 8 (9) e74115, 1-10. doi: 10.1371/journal.pone.0074115
Beverdam, Annemiek, Claxton, Christina, Zhang, Xiaomeng, James, Gregory, Harvey, Kieran F. and Key, Brian (2013). Yap controls stem/progenitor cell proliferation in the mouse postnatal epidermis. Journal of Investigative Dermatology, 133 (6), 1497-1505. doi: 10.1038/jid.2012.430
Conference Papers
Hodges, Paul, James, Greg, Ahern, Ben and Goss, Ben (2024). Targeted Multifidus Muscle Activation Reduces Fibrosis of the Multifidus Muscle Following Intervertebral Disc Injury. North American Neuromodulation Society 27th Annual Meeting, Las Vegas, NV United States, 18-21 January 2024. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.neurom.2024.06.302
Hodges, Paul, James, Greg P., Sluka, Kathleen A., Little, Christopher B., Hall, Leanne, Shu, Cindy C., Blomster, Linda V., Schmid, Annina and Melrose, James (2017). Macrophage Transformation Explains Local Inflammation and Structural Change in the Multifidus Muscle after Intervertebral Disc Injury. NASS Annual Meeting Proceedings, Orlando, FL, United States, 25-28 October 2017. Amsterdam, Netherlands: Elsevier . doi: 10.1016/j.spinee.2017.07.163
Hodges, P., James, G., Blomster, L., Hall, L., Schmid, A., Shu, C., Little, C. and Melrose, J. (2015). Multifidus muscle undergoes structural remodeling of muscle, adipose and connective tissue, but not atrophy after injury: molecular and morphological evidence. World Confederation for Physical Therapy Congress, Singapore, 1-4 May 2015. London, United Kingdom: Elsevier. doi: 10.1016/j.physio.2015.03.3404
Thesis
James, Gregory (2013). Genetic networks underlying neural circuit formation. PhD Thesis, School of Biomedical Sciences, The University of Queensland.